The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
Dec. 27, 2018
General Automation Lab Technologies, Inc., San Carlos, CA (US);
Paul C. Blainey, Cambridge, MA (US);
Michael W. Seely, San Diego, CA (US);
Roman Stocker, Zurich, CH;
Karsten Zengler, Cardiff by the Sea, CA (US);
Scott Conradson, Los Altos Hills, CA (US);
Peter Christey, San Francisco, CA (US);
Alexander Hallock, Redwood City, CA (US);
GENERAL AUTOMATION LAB TECHNOLOGIES INC., San Carlos, CA (US);
Abstract
A method of screening for at least one biological entity of interest using a microfabricated device which has a top surface defining an array of microwells. A sample is loaded onto the microfabricated device such that at least one microwell of the array of microwells includes at least one cell and an amount of a nutrient. A membrane is applied to the microfabricated device to retain the at least one cell and the nutrient. A plurality of cells is cultured from the at least one cell in the at least one microwell of the array of microwells. The plurality of cells in the at least one microwell of the array of microwells are split into a first portion of the plurality of cells and a second portion of the plurality of cells. The plurality of cells is analyzed to determine a presence or absence of a biological entity of interest.