The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
Mar. 27, 2018
Applicant:
Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);
Inventors:
Todd M. Kinsella, Redwood City, CA (US);
Ramesh Bhatt, Belmont, CA (US);
Kristen Baltgalvis, Millbrae, CA (US);
Assignee:
RIGEL PHARMACEUTICALS, INC., South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61P 21/06 (2006.01); A61K 47/61 (2017.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); C07K 14/71 (2006.01); C07K 14/475 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61K 39/3955 (2013.01); A61K 47/542 (2017.08); A61K 47/543 (2017.08); A61K 47/60 (2017.08); A61K 47/61 (2017.08); A61P 21/06 (2018.01); C07K 14/475 (2013.01); C07K 14/71 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present disclosure provides antibodies that specifically bind to and block signaling by ACVR2A, i.e., ACVR2A but not ACVR2B, as well as methods for using the same. The antibodies may be used for the treatment of a number of conditions associated with muscle atrophy, as well as other conditions.