The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
Nov. 14, 2017
Applicant:
Bayer Healthcare Llc, Indianola, PA (US);
Inventors:
Alan Brooks, Clayton, CA (US);
Richard Feldman, El Cerrito, CA (US);
Jian-Ming Gu, Lafayette, CA (US);
Shaun Lippow, San Carlos, CA (US);
Shujun Yuan, Daly City, CA (US);
Peter Bringmann, Concord, CA (US);
Assignee:
Bayer HealthCare LLC, Whippany, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 14/755 (2006.01); A61P 7/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/755 (2013.01); A61P 7/04 (2018.01); C07K 16/2896 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/622 (2013.01); C07K 2317/64 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01); C07K 2319/50 (2013.01);
Abstract
Targeted Factor VIII molecules comprising a Factor VIII linked with at least one domain that specifically binds to a membrane protein on a red blood cell is provided. The disclosed targeted coagulation factors prolong their duration of action and thus, are an improvement for the treatment of hematological diseases such as hemophilia A.