The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 31, 2021

Filed:

Oct. 21, 2019
Applicants:

Fraunhofer-gesellschaft Zur Förderung Der Angewandten Forschung E.v., Munich, DE;

Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd., Jerusalem, IL;

Inventors:

Anke Burger-Kentischer, Stuttgart, DE;

Angela Mattes, Vaihingen, DE;

Maria Zatsepin, Jerusalem, IL;

Amriam Goldblum, Jerusalem, IL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4155 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01); A61K 31/517 (2006.01); A61K 31/5377 (2006.01); C07D 471/04 (2006.01); C07D 413/12 (2006.01); C07D 239/94 (2006.01); C07D 405/04 (2006.01); C07D 295/13 (2006.01); A61P 37/00 (2006.01); C07D 231/12 (2006.01); C07D 401/04 (2006.01); C07D 401/10 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 407/04 (2006.01); C07D 407/14 (2006.01); C07D 413/14 (2006.01); G01N 33/94 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4155 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/5377 (2013.01); A61P 37/00 (2018.01); C07D 231/12 (2013.01); C07D 239/94 (2013.01); C07D 295/13 (2013.01); C07D 401/04 (2013.01); C07D 401/10 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01); C07D 405/04 (2013.01); C07D 407/04 (2013.01); C07D 407/14 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); G01N 33/94 (2013.01); G01N 2333/70596 (2013.01); G01N 2500/04 (2013.01);
Abstract

A method of preventing or treating a disease characterized by an excessive immune response in a subject in need thereof is provided. The method includes administering to the subject a composition including an active component, wherein the active component is a first compound, a second compound, a third compound, a pharmaceutically acceptable salt thereof, a solvate thereof, or a combination thereof, wherein the first, second, and third compounds include: respectively.


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