The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
Oct. 23, 2019
Applicant:
Georgetown University, Washington, DC (US);
Inventors:
Milton L. Brown, Brookeville, MD (US);
Shujie Hou, Gaithersburg, MD (US);
Partha Banerjee, Rockville, MD (US);
Karishma Amin, San Francisco, CA (US);
Assignee:
GEORGETOWN UNIVERSITY, Washington, DC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/88 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); A61K 31/403 (2006.01);
U.S. Cl.
CPC ...
C07D 209/88 (2013.01); A61K 31/403 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract
Small molecule carbazole compounds for use as androgen receptor inhibitors are provided herein. Also provided herein are methods for using the carbazole compounds in treating prostate cancer, including castration-resistant prostate cancer and enzalutamide-resistant prostate cancer. The methods include administering to a subject an effective amount of a compound or composition as described herein.