The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 31, 2021

Filed:

Jul. 14, 2017
Applicant:

Puridify Ltd., Hertfordshire, GB;

Inventor:

Ian Scanlon, Cambridgeshire, GB;

Assignee:

Puridify Ltd., Hertfordshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J 20/285 (2006.01); A61P 35/00 (2006.01); A61K 48/00 (2006.01); B01J 20/28 (2006.01); C12N 7/00 (2006.01); C12N 7/02 (2006.01);
U.S. Cl.
CPC ...
B01J 20/285 (2013.01); A61K 48/0091 (2013.01); A61P 35/00 (2018.01); B01J 20/28038 (2013.01); C12N 7/00 (2013.01); C12N 7/02 (2013.01); C12N 2710/10051 (2013.01); C12N 2750/14151 (2013.01); C12N 2799/022 (2013.01); C12N 2799/025 (2013.01);
Abstract

The present invention provides a process for recovering a viral product from a composition comprising said product and product-related impurities, which process comprises contacting the composition with a functionalised chromatography medium comprising one or more polymer nanofibres, wherein the viral product comprises a plurality of viruses, virus particles/virions, viral cores, membrane-stripped viruses, viral cores with outer membrane(s) removed and/or capsids removed, or proviruses, each of which contains one or more polynucleotides, and wherein the product-related impurities comprise a plurality of viruses, virus particles/virions, virus-like particles, viral cores, membrane-stripped viruses, viral cores with outer membrane(s) removed and/or capsids removed or proviruses, each of which is substantially devoid of polynucleotides.


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