The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 31, 2021

Filed:

Oct. 23, 2015
Applicants:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Circuit Therapeutics, Inc., Menlo Park, CA (US);

Inventors:

Karl A. Deisseroth, Stanford, CA (US);

Elizabeth R. Aden, Berkeley, CA (US);

Viviana Gradinaru, Menlo Park, CA (US);

Scott L. Delp, Stanford, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61N 5/06 (2006.01); A61K 48/00 (2006.01); A61K 49/00 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61N 5/062 (2013.01); A61K 38/177 (2013.01); A61K 48/005 (2013.01); A61K 49/0008 (2013.01); A61N 2005/0663 (2013.01); C12N 2750/14141 (2013.01);
Abstract

Provided herein are methods for the treatment of bladder dysfunction, including detrusor hyperreflexia and detrusor external sphincter dyssynergia, fecal incontinence, and/or sexual dysfunction in an individual via the use of stably expressed light-responsive opsin proteins capable of selective hyperpolarization or depolarization of the neural cells that innervate the muscles responsible for physiologic functioning of urinary bladder, external urinary sphincter, external anal sphincter, and the male and female genitalia.


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