The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
May. 01, 2020
Aruna Gambhir;
Edwin Chang, Menlo Park, CA (US);
Chirag B. Patel, Palo Alto, CA (US);
Sanjiv S. Gambhir, Portola Valley, CA (US);
Tali Voloshin-Sela, Kibbutz Gvat, IL;
Yaara Porat, Kibbutz Gvat, IL;
Moshe Giladi, Moshav Herut, IL;
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Novocure GmbH, Root, CH;
Abstract
Certain substances (e.g., large molecules) that ordinarily cannot traverse the cell membrane of cells can be introduced into cells by applying an alternating electric field to the cell for a period of time, wherein the frequency of the alternating electric field is selected so that application of the alternating electric field increases permeability of the cell membrane. Once the permeability of the cell membrane has been increased, the substance is able to cross the cell membrane. This approach is particularly useful in the context of cancer cells (e.g., glioblastoma).