The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 31, 2021

Filed:

Nov. 17, 2017
Applicants:

Japan As Represented BY the Director-general of National Institute of Infectious Diseases, Tokyo, JP;

ID Pharma Co., Ltd., Tokyo, JP;

Inventors:

Tetsuro Matano, Tokyo, JP;

Makoto Inoue, Tokyo, JP;

Hiroto Hara, Tokyo, JP;

Tsugumine Shu, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/21 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/21 (2013.01); C12N 7/00 (2013.01); C12N 2740/10022 (2013.01); C12N 2740/10034 (2013.01); C12N 2760/18823 (2013.01); C12N 2760/18843 (2013.01);
Abstract

In this invention, a non-infectious particle has been produced, comprising a pathogen antigen protein caused to be expressed on the surface of a virus particle having at least one species of paramyxovirus envelope protein missing from the particle. This particle has been found to hold within the particle a large amount of antigen protein compared to an infectious particle, and to be capable of eliciting a host immune response with extremely high efficiency. The non-infectious particle according to the present invention is useful as a vaccine against a pathogenic virus, or the like.


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