The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
Jun. 14, 2019
Applicant:
Academia Sinica, Taipei, TW;
Inventors:
Shih-Hsiung Wu, Taipei, TW;
Chung-Yi Wu, Taipei, TW;
I-Ming Lee, Taipei, TW;
Feng-Ling Yang, Taipei, TW;
Assignee:
ACADEMIA SINICA, Taipei, TW;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/05 (2006.01); A61K 45/06 (2006.01); A61P 31/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/05 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); A61K 2039/6037 (2013.01); A61K 2039/627 (2013.01);
Abstract
Disclosed herein is a glycoconjugate vaccine conferring protection against a Gram negative pathogen infection, a method of manufacturing the glycoconjugate vaccine, and use of the glycoconjugate vaccine for treating bacterial infection. The glycoconjugate vaccine of the present disclosure has the structure of formula (I), wherein, L is a maleimide-type linker, which is connected to the carrier protein via a maleimide bond formed therebetween; and n and m are independently an integral or a non-integral number between 2 and 20.