The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
Jan. 17, 2020
Zonhon Biopharma Institute Inc., Changzhou, CN;
Gensun Institute of Biomedicine Co., Ltd., Changzhou, CN;
Bruce Yong Ma, Changzhou, CN;
Jun Wang, Changzhou, CN;
He Wang, Changzhou, CN;
Chunlin Xu, Changzhou, CN;
Yifei Chen, Changzhou, CN;
Yaofang Wang, Changzhou, CN;
ZONHON BIOPHARMA INSTITUTE INC., Changzhou, CN;
GENSUN INSTITUTE OF BIOMEDICINE CO., LTD., Changzhou, CN;
Abstract
The present application discloses a PEGylated asparaginase and use thereof. In this application, the polyethylene glycol (PEG) is coupled to the N-terminal amino of 1 or 2 subunits of L-asparaginase, and the molecular weight of the PEG is 30-40 KDa. The PEG is preferably branched and has an aldehyde serving as an activating group. The PEGylated asparaginase is useful in the preparation of anti-tumor drugs.