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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11103559 B1

PDFFull Text
Date of Patent:
Aug. 31, 2021

Filed:

Apr. 10, 2020

Pharmaceutical compositions and methods

Applicant:

Tyme, Inc., New York, NY (US);

Inventor:

Steven Hoffman, Mahwah, NJ (US);

Assignee:

Tyme, Inc., Mahwah, NJ (US);

Attorney:

BakerHostetler

Primary Examiner:

Julie Ha

Assistant Examiner:

Kristina M Hellman

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 35/00 (2006.01); A61K 38/34 (2006.01); A61K 9/48 (2006.01); A61K 31/19 (2006.01); A61K 31/198 (2006.01); A61K 31/216 (2006.01); A61K 31/366 (2006.01); A61K 31/436 (2006.01); A61K 9/10 (2006.01); A61K 31/55 (2006.01); A61K 31/787 (2006.01); A61K 38/12 (2006.01); A61K 9/00 (2006.01); A61K 31/4166 (2006.01);
U.S. Cl.
CPC ...
A61K 38/34 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 9/10 (2013.01); A61K 9/48 (2013.01); A61K 31/19 (2013.01); A61K 31/198 (2013.01); A61K 31/216 (2013.01); A61K 31/366 (2013.01); A61K 31/4166 (2013.01); A61K 31/436 (2013.01); A61K 31/55 (2013.01); A61K 31/787 (2013.01); A61K 38/12 (2013.01);
Abstract

Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided. Also provided are methods of treating cancer in a subject, comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof. Also provided are methods of reducing cell proliferation in a subject comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof.

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