The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
Feb. 06, 2018
Per Svenningsson, Stockholm, SE;
Lina Leinartaite, Vilnius, LT;
Magdalena Otrocka, Gnesta, SE;
Vedran Hasimbegovic, Handen, SE;
Birgitta Pettersson, Hagersten, SE;
Per Svenningsson, Stockholm, SE;
Lina Leinartaite, Vilnius, LT;
Magdalena Otrocka, Gnesta, SE;
Vedran Hasimbegovic, Handen, SE;
Birgitta Pettersson, Hagersten, SE;
Other;
Abstract
The invention relates to compounds that are useful in the treatment of parkinsonism, such as parkinsonism in connection with Parkinson's disease (PD); dementia with Lewy bodies (DLB); multiple system atrophy (MSA); corticobasal degeneration (CBD); or progressive supranuclear palsy (PSP). The said compounds include in particular idoxuridine and analogs thereof as well as their metabolic precursors, such as ropidoxuridine. The invention further relates to method for identifying compounds useful for the treatment of parkinsonism, said methods comprising detecting the capability of compound to increase the amount of GPR37 in cell membranes. The invention further relates to methods for the chemical synthesis of ropidoxuridine.