The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
Feb. 13, 2020
Asana Biosciences, Llc, Lawrenceville, NJ (US);
Aranapakam M. Venkatesan, Rego Park, NY (US);
Scott K. Thompson, Phoenixville, PA (US);
Roger A. Smith, Chester Springs, PA (US);
Sanjeeva P. Reddy, Chester Springs, PA (US);
Raghava Reddy Kethiri, Bangalore, IN;
Purushottam M. Dewang, Bangalore, IN;
Gurulingappa Hallur, Bangalore, IN;
Chandrika Mulakala, Bangalore, IN;
ASANA BIOSCIENCES, LLC, Lawrenceville, NJ (US);
Abstract
The present application provides novel heterocyclic compounds and pharmaceutically acceptable salts thereof. Also provided are methods for preparing these compounds. These compounds are useful for inhibiting ERK1/2. By administering to a patient in need a therapeutically effective amount of one or more of the compounds of formula (I), wherein X, Y, Z, J, M, and Rto Rare defined herein, these compounds are effective in treating conditions associated with dysregulation of the RAS/RAF/MEK/ERK pathway. A variety of conditions can be treated using these compounds and include diseases which are characterized by abnormal cellular proliferation. In one embodiment, the disease is cancer.