The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
Apr. 23, 2019
Applicant:
Corium, Inc., Grand Rapids, MI (US);
Inventors:
Eun Soo Lee, Redwood City, CA (US);
Amit K. Jain, Milpitas, CA (US);
Parminder Singh, Union City, CA (US);
Assignee:
Corium, Inc., Grand Rapids, MI (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/70 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61K 47/32 (2006.01); A61K 31/27 (2006.01); A61K 31/18 (2006.01); A61K 31/137 (2006.01); A61K 31/13 (2006.01); A61K 31/445 (2006.01); C08K 5/00 (2006.01); A61K 47/02 (2006.01); A61K 31/00 (2006.01); A61K 31/045 (2006.01);
U.S. Cl.
CPC ...
A61K 9/7038 (2013.01); A61K 9/7023 (2013.01); A61K 9/7053 (2013.01); A61K 9/7061 (2013.01); A61K 9/7084 (2013.01); A61K 9/7092 (2013.01); A61K 31/00 (2013.01); A61K 31/13 (2013.01); A61K 31/137 (2013.01); A61K 31/18 (2013.01); A61K 31/27 (2013.01); A61K 31/445 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/32 (2013.01); C08K 5/0016 (2013.01); A61K 31/045 (2013.01);
Abstract
A transdermal delivery system for systemic delivery of donepezil is described, where the system comprises an adhesive matrix drug reservoir layer comprised of a copolymer of acrylic acid/vinyl acetate, triethyl citrate, and donepezil base generated in situ by reaction of donepezil HCl and an alkaline salt. The system is provided for treatment of Alzheimer's disease, and achieves transdermal delivery of the therapeutic agent at steady state that is bioequivalent to administration of the therapeutic agent orally.