The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2021

Filed:

Jun. 14, 2018
Applicant:

Nooma Bio, Inc., Santa Cruz, CA (US);

Inventors:

Reto Stamm, Half Moon Bay, CA (US);

Michael Summers, Santa Cruz, CA (US);

Eric Thorne, Santa Cruz, CA (US);

William B. Dunbar, Santa Cruz, CA (US);

Assignee:

Nooma Bio, Inc., Santa Cruz, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/487 (2006.01); C12Q 1/6869 (2018.01); G01N 27/447 (2006.01); B82Y 30/00 (2011.01); B82Y 15/00 (2011.01);
U.S. Cl.
CPC ...
G01N 33/48721 (2013.01); C12Q 1/6869 (2013.01); G01N 27/44743 (2013.01); G01N 27/44791 (2013.01); B82Y 15/00 (2013.01); B82Y 30/00 (2013.01);
Abstract

Two-pore devices and method for sequencing are described. A two-pore device can include first chamber, a second chamber, and a third chamber, wherein the first chamber is in communication with the second chamber through a first nanopore, and wherein the second chamber is in communication with the third chamber through a second nanopore. The device can also include sensing circuitry for measuring electrical signals associated with a target at a nanopore, and control circuitry for controlling motion of the target at a nanopore. The device can include and/or switch between sensing and control modes for each of the first nanopore and the second nanopore. Sequencing methods can implement a two-pore device in relation to translocation of a target through one or more nanopores, switching between sensing and control modes as appropriate, and measuring aspects of the target using in sensing modes.


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