The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2021

Filed:

Nov. 29, 2016
Applicant:

Shimadzu Corporation, Kyoto, JP;

Inventor:

Manabu Ueda, Kyoto, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
H01J 49/16 (2006.01); G01N 30/72 (2006.01); G01N 27/62 (2021.01); H01J 49/04 (2006.01); H01J 49/10 (2006.01);
U.S. Cl.
CPC ...
G01N 30/726 (2013.01); G01N 27/62 (2013.01); G01N 30/7266 (2013.01); H01J 49/04 (2013.01); H01J 49/10 (2013.01); H01J 49/167 (2013.01); H01J 49/168 (2013.01);
Abstract

An ionizer includes an ionization probe () provided with a capillary (), a metallic slender tube (), and a nebulizing gas pipe (). The ionization probe () is equipped to perform ESI-based ionization of components in a liquid sample. An electroconductive capillary () is disposed at a position forward in a flow direction of a nebulized flow of the liquid sample from the ionization probe (). A high voltage from a high voltage power supply () is applied to the electroconductive capillary () to induce corona discharge so that the components in the liquid sample are ionized by the APCI as well. At the time of tuning the ionizer, a standard sample solution is provided through the electroconductive capillary (), and a high voltage from the high voltage power supply () is applied to the electroconductive capillary () so that components in the standard sample solution are ionized by the ESI or due to an ion molecular reaction with solvent molecular ions produced in the ionization probe (). Thus, components in a standard sample can be ionized and subjected to mass spectrometry without pipe rearranging operations or without switch to and from different flow paths using a valve.


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