The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2021

Filed:

Dec. 01, 2016
Applicants:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Owlstone Medical Limited, Cambridgeshire, GB;

Inventors:

Uwe Kobold, Weilheim, DE;

Roland Thiele, Obersoechering, DE;

Noah Weiss, Munich, DE;

Lauren Brown, Cambridgeshire, GB;

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/624 (2021.01); G01N 33/82 (2006.01); G01N 33/487 (2006.01); H01J 49/00 (2006.01);
U.S. Cl.
CPC ...
G01N 27/624 (2013.01); G01N 33/487 (2013.01); G01N 33/82 (2013.01); H01J 49/0031 (2013.01);
Abstract

A method of quantifying the amount of at least two analytes A1 and A2 involving (a) adding at least one salt (S) to at least a portion (P1) of the sample comprising the at least two analytes A1 and A2, (b) ionizing at least a portion of the sample according to (a) thereby forming an analyte flow comprising the analytes A1 and A2 in ionized form, (c) separating the ionized analytes A1 and A2 from each other by using at least one ion mobility separator (), wherein the analyte flow according to (b) at least partially passes through the ion mobility separator (), and (d) quantifying the amount of the separated ionized analytes obtained according to (c), wherein A1 is a pharmaceutically active compound C or derivative thereof and A2 is a metabolite or stereoisomer of C.


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