The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2021
Filed:
Dec. 04, 2018
Applicant:
Synthetic Genomics, Inc., La Jolla, CA (US);
Inventor:
Imad Ajjawi, San Diego, CA (US);
Assignee:
Synthetic Genomics, Inc., La Jolla, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/64 (2006.01); C12N 15/82 (2006.01); C07K 14/405 (2006.01);
U.S. Cl.
CPC ...
C12P 7/64 (2013.01); C07K 14/405 (2013.01); C12N 15/8247 (2013.01); C12N 15/8216 (2013.01);
Abstract
The present invention provides mutant microorganisms having attenuated expression of a gene encoding a polypeptide that includes a GAF domain wherein the mutant microorganisms have higher lipid productivity and/or exhibit increased partitioning of carbon to lipid as compared to wild-type microorganisms from which they are derived. Also provided are methods of producing lipids using the mutant microorganisms, guide RNAs, and nucleic acid constructs used for producing mutant microorganisms.