The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2021
Filed:
Sep. 05, 2019
Applicant:
Regents of the University of Minnesota, Minneapolis, MN (US);
Inventors:
Daniel Attilio Vallera, Richfield, MN (US);
Jeffrey S. Miller, Little Canada, MN (US);
Assignee:
Regents of the University of Minnesota, Minneapolis, MN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); C07K 14/55 (2006.01); C07K 14/54 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C07K 16/10 (2006.01); C07K 16/24 (2006.01); C12N 5/0783 (2010.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/55 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07K 14/5443 (2013.01); C07K 16/1045 (2013.01); C07K 16/244 (2013.01); C07K 16/283 (2013.01); C07K 16/2803 (2013.01); C07K 16/2809 (2013.01); C07K 16/30 (2013.01); C12N 5/0646 (2013.01); A61K 38/00 (2013.01); C07K 2317/22 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/622 (2013.01); C07K 2319/33 (2013.01);
Abstract
This disclosure describes engineered compounds that engage NK cells and methods of using the compounds. Generally, the compound includes an NK engaging domain, a targeting domain that selectively binds to a target cell, and an NK activating domain operably linking the NK engaging domain and the targeting domain.