The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2021

Filed:

Jul. 05, 2018
Applicants:

The United States of America,as Represented BY the Secretary,department of Health and Human Services, Bethesda, MD (US);

Fundacio Institut Catala D'investigacio Quimica, Tarragona, ES;

University of Delaware, Newark, DE (US);

University of Leeds, Leeds, GB;

Universitat Rovira I Virgili, Tarragona, ES;

Inventors:

John A. Beutler, Union Bridge, MD (US);

Antonio Echavarren, Tarragona, ES;

William Chain, Newark, DE (US);

David Beech, Leeds, GB;

Zhenhua Wu, Newark, DE (US);

Jean-Simon Suppo, Tarragona, ES;

Fernando Bravo, Tarragona, ES;

Hussein Rubaiy, Leeds, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 493/08 (2006.01); A61P 35/00 (2006.01); C07D 495/08 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
C07D 493/08 (2013.01); A61P 35/00 (2018.01); C07D 471/08 (2013.01); C07D 495/08 (2013.01);
Abstract

Disclosed is a compound of formula (I) in which a, R-Rand Xare as described herein. Also disclosed are a pharmaceutical composition containing the compound and a method of using the compound for treating cancer, such as renal cancer.


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