The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2021

Filed:

Jul. 14, 2017
Applicant:

Puridify Ltd., Hertfordshire, GB;

Inventors:

Marc Hummersone, Hertfordshire, GB;

Benjamin Wallis, Hertfordshire, GB;

Frederic Leroux, Greater London, GB;

William Law, Cambridgeshire, GB;

Assignee:

Puridify Ltd., Hertfordshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/20 (2006.01); B01D 15/38 (2006.01); B01J 20/26 (2006.01); B01J 20/28 (2006.01); B01J 20/286 (2006.01); B01J 20/289 (2006.01); B01J 20/30 (2006.01); B01J 20/32 (2006.01); C07K 1/16 (2006.01);
U.S. Cl.
CPC ...
B01J 20/265 (2013.01); B01D 15/20 (2013.01); B01D 15/3809 (2013.01); B01J 20/286 (2013.01); B01J 20/289 (2013.01); B01J 20/28023 (2013.01); B01J 20/28038 (2013.01); B01J 20/28052 (2013.01); B01J 20/3085 (2013.01); B01J 20/3092 (2013.01); B01J 20/321 (2013.01); B01J 20/328 (2013.01); B01J 20/3212 (2013.01); B01J 20/3217 (2013.01); B01J 20/3219 (2013.01); B01J 20/3227 (2013.01); B01J 20/3248 (2013.01); B01J 20/3272 (2013.01); B01J 20/3293 (2013.01); C07K 1/16 (2013.01); B01J 2220/62 (2013.01);
Abstract

The present invention provides a functionalised polymeric chromatography medium, prepared by a process which comprises (i) providing a substrate formed of one or more polymer nanofibres, (ii) grafting one or more neutral polymer chains from the substrate, and (iii) contacting the grafted product with a reagent which functionalises the product of step (ii) as a chromatography medium, wherein step (ii) comprises reacting a plurality of compounds of formula and/or its enantiomers, and/or its derivatives of formula (I) and/or enantiomers and/or diastereomers thereof: with one or more functional groups present on the nanofibre substrate, wherein R, R, R, Rand Rmay be the same or different, and are chosen from H, halogen, C-Calkyl, or C-Calkoxy provided that at least one of R, R, R, Ror Ris not hydrogen.


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