The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2021
Filed:
Dec. 09, 2016
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Michael Ortiz, Pasadena, CA (US);
Stefanie Heyden, Pasadena, CA (US);
Assignee:
California Institute of Technology, Pasadena, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61N 7/00 (2013.01); A61N 2007/0004 (2013.01);
Abstract
Systems and methods for targeting specific cell types by selective application of ultrasonic harmonic excitation at their resonance frequency ('oncotripsy') are presented. The systems and methods result in the lysis of targeted cell types by using ultrasonic harmonic excitations that have been specifically tuned to disrupt the nuclear membrane of the targeted cells types by inducing a destructive vibrational response therein while leaving non-targeted cell types intact. The target cells types may be cancerous cells.