logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11097034 B1

PDFFull Text
Date of Patent:
Aug. 24, 2021

Filed:

Dec. 11, 2017

Compositions and methods of modulating endochondral ossification and bone formation

Applicants:

Case Western Reserve Univeristy, Cleveland, OH (US);

University of California, San Francisco, San Francisco, CA (US);

Inventors:

Eben Alsberg, Cleveland, OH (US);

Oju Jeon, Cleveland, OH (US);

Ralph Marcucio, San Francisco, CA (US);

Chelsea Bahney, San Francisco, CA (US);

Diane Hu, San Francisco, CA (US);

Sarah Knox, San Francisco, CA (US);

Assignees:

CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);

Attorney:

Tarolli, Sundheim, Covell & Tummino LLP

Primary Examiner:

Zohreh A Fay

Int. Cl.
CPC ...
A61K 31/221 (2006.01); A61K 31/5578 (2006.01); A61L 27/38 (2006.01); A61K 35/28 (2015.01); A61K 38/20 (2006.01); A61K 35/32 (2015.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3847 (2013.01); A61K 31/221 (2013.01); A61K 31/5578 (2013.01); A61K 35/28 (2013.01); A61K 35/32 (2013.01); A61K 38/204 (2013.01); A61K 38/2093 (2013.01); A61L 27/3817 (2013.01); A61L 27/3852 (2013.01); A61K 45/06 (2013.01); A61L 2300/426 (2013.01); A61L 2300/432 (2013.01); A61L 2430/02 (2013.01); A61L 2430/06 (2013.01);
Abstract

A method of modulating transdifferentiation of chondrocytes to osteoblast includes administering to the chondrocytes an agent that modulates GP130 receptor signaling and expression of at least one of Sox2, Oct4, or Nanog of the chondrocytes.

Find Patent Forward Citations

Alsberg, Eben. (2021). Compositions and methods of modulating endochondral ossification and bone formation (U.S. Patent No. 11097034). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11097034

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…