The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2021

Filed:

Feb. 12, 2016
Applicant:

Kyoto University, Kyoto, JP;

Inventors:

Hiroshi Sugiyama, Kyoto, JP;

Toshikazu Bando, Kyoto, JP;

Assignee:

KYOTO UNIVERSITY, Kyoto, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/167 (2006.01); A61K 47/59 (2017.01); C07D 207/34 (2006.01); A61K 31/787 (2006.01); C07D 403/14 (2006.01); A61K 45/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/595 (2017.08); A61K 31/167 (2013.01); A61K 31/787 (2013.01); A61K 45/00 (2013.01); C07D 207/34 (2013.01); C07D 403/14 (2013.01);
Abstract

The present invention provides: a histone modification control agent for activating expression of a specific gene, i.e., a complex including a histone acetylation enzyme activator useful as an agent for activating a specific gene, and a polyamide for recognizing a regulatory region of a target gene; and a method for manufacturing the same. This complex specifically activates a group of genes relating to maintenance and/or differentiation of stem cells or precursor cells.


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