The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2021

Filed:

Nov. 10, 2017
Applicant:

Deutsches Krebsforschungszentrum, Heidelberg, DE;

Inventors:

Henri-Jacques Delecluse, Heidelberg, DE;

Anatoliy Shumilov, Heidelberg, DE;

Ming-Han Tsai, Taoyuan, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/245 (2006.01); A61P 31/22 (2006.01); C12N 7/00 (2006.01); A61K 39/12 (2006.01);
U.S. Cl.
CPC ...
A61K 39/245 (2013.01); A61K 39/12 (2013.01); A61P 31/22 (2018.01); C12N 7/00 (2013.01); C12N 2710/16223 (2013.01); C12N 2710/16234 (2013.01);
Abstract

The present invention relates to a composition comprising Epstein-Barr Virus (EBV) particles for use in vaccination of a subject, wherein said EBV particles comprise a significantly reduced chromosome instability-inducing EBV polypeptide activity. The present invention also relates to a composition comprising EBV particles for use in vaccination of a subject, wherein said vaccination comprises avoiding contacting the cytosol and/or nucleus of cells of said subject with a chromosome instability-inducing EBV polypeptide activity. Moreover, the present invention relates to polynucleotides, host cells, methods, and uses related to the aforesaid compositions.


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