The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2021

Filed:

Mar. 04, 2016
Applicant:

Probiotical S.p.a., Novara, IT;

Inventor:

Giovanni Mogna, Novara, IT;

Assignee:

PROBIOTICAL S.P.A., Novara, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/60 (2006.01); A61K 36/28 (2006.01); A61K 31/136 (2006.01); A61K 31/337 (2006.01); A61K 31/365 (2006.01); A61K 31/4741 (2006.01); A61K 31/4745 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01); A61K 31/555 (2006.01); A61K 31/675 (2006.01); A61K 31/704 (2006.01); A61K 31/7048 (2006.01); A61K 33/24 (2019.01); A61K 36/29 (2006.01); A61K 36/66 (2006.01);
U.S. Cl.
CPC ...
A61K 36/28 (2013.01); A61K 31/136 (2013.01); A61K 31/337 (2013.01); A61K 31/365 (2013.01); A61K 31/4741 (2013.01); A61K 31/4745 (2013.01); A61K 31/513 (2013.01); A61K 31/519 (2013.01); A61K 31/555 (2013.01); A61K 31/675 (2013.01); A61K 31/704 (2013.01); A61K 31/7048 (2013.01); A61K 33/24 (2013.01); A61K 36/29 (2013.01); A61K 36/66 (2013.01); A61K 2300/00 (2013.01);
Abstract

The use of at least one flavonoid of natural or synthetic origin in association with cyclophosphamide and/or methotrexate to increase the effectiveness of chemotherapeutic treatments used in human and veterinary medicine for the treatment of tumors is described, in particular in case of resistance to the chemotherapeutic agents currently in use. At least one flavonoid herein described is selected from the group comprising or, alternatively, consisting of rutin, oxerutin, diosmin, troxerutin and hesperidin.


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