The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2021

Filed:

Apr. 04, 2017
Applicants:

The Regents of the University of California, Oakland, CA (US);

Ulm University, Ulm, DE;

Inventors:

Samuel J. Balin, Playa Del Rey, CA (US);

Robert L. Modlin, Sherman Oaks, CA (US);

Steffen Stenger, Ulm, DE;

Matteo Pellegrini, Sherman Oaks, CA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); G01N 33/569 (2006.01); G01N 33/50 (2006.01); C12N 5/0783 (2010.01); A61K 38/20 (2006.01); C12Q 1/6883 (2018.01); C12Q 1/6886 (2018.01); A61K 45/06 (2006.01); C07K 16/28 (2006.01); C12Q 1/6888 (2018.01); G01N 15/06 (2006.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 38/20 (2013.01); A61K 38/2013 (2013.01); A61K 38/2046 (2013.01); A61K 38/2086 (2013.01); A61K 45/06 (2013.01); C07K 16/2866 (2013.01); C12N 5/0638 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/6886 (2013.01); C12Q 1/6888 (2013.01); G01N 15/0656 (2013.01); G01N 33/505 (2013.01); G01N 33/56972 (2013.01); C12Q 2600/158 (2013.01); G01N 2015/008 (2013.01); G01N 2015/0693 (2013.01); G01N 2800/24 (2013.01);
Abstract

Various aspects of the invention relate to compositions comprising polycytotoxic T cells. Some aspects relate to methods for obtaining a composition comprising polycytotoxic T cells. Some aspects relate to methods of administering a composition comprising polycytotoxic T cells to a subject. Some aspects relate to methods for monitoring an immune response in a subject, comprising determining the concentration of polycytotoxic T cells in the blood of the subject. Some aspects relate to methods for treating a condition or disease in a subject, comprising administering to the subject a composition comprising an antibody, or an antigen-binding portion thereof, that specifically binds to a protein expressed by a polycytotoxic T cell.


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