The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2021

Filed:

Apr. 24, 2017
Applicant:

Iomet Pharma Ltd., Scotland, GB;

Inventors:

Phillip M. Cowley, Edinburgh, GB;

Meredeth Ann McGowan, Boston, MA (US);

Thomas J. Brown, Edinburgh, GB;

Yongxin Han, Needham, MA (US);

Kun Liu, Needham, MA (US);

Qinglin Pu, Needham, MA (US);

Alan Wise, Scotland, GB;

Hongjun Zhang, Boston, MA (US);

Hua Zhou, Acton, MA (US);

Assignees:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

IOmet Pharma Ltd., Edinburgh, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); A61K 31/438 (2006.01);
U.S. Cl.
CPC ...
A61K 31/438 (2013.01); C07D 519/00 (2013.01);
Abstract

Disclosed herein are substituted imidazopyridine compounds of formula (I) which are inhibitors of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan-2,3-dioxygenase (TDO) enzymes: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder.


Find Patent Forward Citations

Loading…