The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2021
Filed:
Aug. 05, 2020
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Andre E. Nel, Sherman Oaks, CA (US);
Huan Meng, Los Angeles, CA (US);
Xiangsheng Liu, Los Angeles, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/127 (2006.01); A61K 31/4745 (2006.01); A61K 45/06 (2006.01); A61K 47/62 (2017.01); A61K 47/69 (2017.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5115 (2013.01); A61K 9/127 (2013.01); A61K 9/5123 (2013.01); A61K 9/5192 (2013.01); A61K 31/4745 (2013.01); A61K 45/06 (2013.01); A61K 47/62 (2017.08); A61K 47/6923 (2017.08); A61K 47/6929 (2017.08); A61K 9/0019 (2013.01); A61K 9/1278 (2013.01); Y10S 977/773 (2013.01); Y10S 977/906 (2013.01); Y10S 977/907 (2013.01);
Abstract
A nanocarrier including a silica body having a surface and defining a plurality of pores that are suitable to receive molecules therein is described. The nanocarrier also includes a lipid bilayer coating the surface, and a cargo-trapping agent within the phospholipid bilayer. The phospholipid bilayer stably seals the plurality of pores. The cargo-trapping reagent can be selected to interact with a desired cargo, such as a drug.