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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11094424 B1

PDFFull Text
Date of Patent:
Aug. 17, 2021

Filed:

Aug. 29, 2019

Closed evaporation system

Applicant:

GE Healthcare Limited, Buckinghamshire, GB;

Inventors:

Xavier Franci, Loncin, BE;

Steve Lignon, Loncin, BE;

Audrey Lange, Loncin, BE;

Assignee:

GE HEALTHCARE LIMITED, Buckinghamshire, GB;

Attorneys:

Jeff B. Vockrodt

Culhane Meadows, PLLC

Primary Examiner:

Michael G Hartley

Assistant Examiner:

Sean R Donohue

Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); G21F 9/08 (2006.01); G21G 4/08 (2006.01); C07H 19/06 (2006.01); B01J 19/00 (2006.01); C07B 59/00 (2006.01); C07C 227/40 (2006.01); C07D 233/91 (2006.01); C07J 1/00 (2006.01); G21G 1/00 (2006.01); B01D 1/30 (2006.01);
U.S. Cl.
CPC ...
G21F 9/08 (2013.01); B01D 1/30 (2013.01); B01J 19/0093 (2013.01); C07B 59/00 (2013.01); C07B 59/005 (2013.01); C07C 227/40 (2013.01); C07D 233/91 (2013.01); C07H 19/06 (2013.01); C07J 1/007 (2013.01); G21G 1/0005 (2013.01); G21G 4/08 (2013.01); B01J 2219/009 (2013.01); B01J 2219/00799 (2013.01); B01J 2219/00873 (2013.01); B01J 2219/00885 (2013.01); B01J 2219/00959 (2013.01); B01J 2219/00963 (2013.01); C07B 2200/05 (2013.01); C07C 2601/04 (2017.05);
Abstract

The present invention provides a system for evaporating a radioactive fluid, a method for the synthesis of a radiolabelled compound including this system, and a cassette for the synthesis of a radiolabelled compound comprising this system. The present invention provides advantages over known methods for evaporation of a radioactive fluid as it reduces drastically the amount of radioactive gaseous chemicals that are released in the hot cell. It is gentler and more secure compared to the known process and provides access to radiosyntheic processes that may not been acceptable for safety reasons related to release of volatile radioactive gases during evaporation. In addition, the process yields are higher because the radioactive volatiles are labelled intermediate species.

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