The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 17, 2021

Filed:

Jul. 31, 2017
Applicant:

Ventana Medical Systems, Inc., Tucson, AZ (US);

Inventors:

Jerome W. Kosmeder, II, Tucson, AZ (US);

Mark Lefever, Oro Valley, AZ (US);

Donald Johnson, Tucson, AZ (US);

Michael Farrell, Tucson, AZ (US);

Zhanna Zhilina, Tucson, AZ (US);

Christopher Bieniarz, Tucson, AZ (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/532 (2006.01); C07D 495/04 (2006.01); G01N 33/58 (2006.01); G01N 33/53 (2006.01); G01N 33/533 (2006.01); C07D 491/147 (2006.01); C07D 277/76 (2006.01); C07D 241/44 (2006.01); C07D 493/04 (2006.01); C07D 243/12 (2006.01); C07D 277/48 (2006.01); C07D 215/52 (2006.01); C07D 231/16 (2006.01); C07D 493/14 (2006.01); C07D 491/056 (2006.01); C07D 498/04 (2006.01); C07D 311/12 (2006.01); C07D 491/052 (2006.01); C07D 271/12 (2006.01); C07D 417/12 (2006.01); C07D 271/08 (2006.01); C12Q 1/6804 (2018.01); C12Q 1/6841 (2018.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
G01N 33/5308 (2013.01); C07D 215/52 (2013.01); C07D 231/16 (2013.01); C07D 241/44 (2013.01); C07D 243/12 (2013.01); C07D 271/08 (2013.01); C07D 271/12 (2013.01); C07D 277/48 (2013.01); C07D 277/76 (2013.01); C07D 311/12 (2013.01); C07D 417/12 (2013.01); C07D 491/052 (2013.01); C07D 491/056 (2013.01); C07D 491/147 (2013.01); C07D 493/04 (2013.01); C07D 493/14 (2013.01); C07D 495/04 (2013.01); C07D 498/04 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/6841 (2013.01); C12Q 1/6886 (2013.01); G01N 33/532 (2013.01); G01N 33/533 (2013.01); G01N 33/58 (2013.01); G01N 33/582 (2013.01); G01N 33/583 (2013.01); Y10S 435/961 (2013.01); Y10S 530/807 (2013.01);
Abstract

A method for performing a multiplexed diagnostic assay, such as for two or more different targets in a sample, is described. One embodiment comprised contacting the sample with two or more specific binding moieties that bind specifically to two or more different targets. The two or more specific binding moieties are conjugated to different haptens, and at least one of the haptens is an oxazole, a pyrazole, a thiazole, a nitroaryl compound other than dinitrophenyl, a benzofurazan, a triterpene, a urea, athiourea, a rotenoid, a coumarin, a cyclolignan, a heterobiaryl, an azo aryl, or a benzodiazepine. The sample is contacted with two or more different anti-hapten antibodies that can be detected separately. The two or more different anti-hapten antibodies may be conjugated to different detectable labels.


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