The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 17, 2021

Filed:

Feb. 06, 2020
Applicant:

Caris Science, Inc., Irving, TX (US);

Inventors:

Heather O'Neill, Mesa, AZ (US);

Mark Miglarese, Phoenix, AZ (US);

David Spetzler, Paradise Valley, AZ (US);

Assignee:

Caris Science, Inc., Irving, TX (US);

Attorney:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/115 (2010.01); A61K 31/711 (2006.01); A61K 47/68 (2017.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); A61K 31/711 (2013.01); A61K 47/6807 (2017.08); G01N 33/53 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3513 (2013.01); C12N 2320/10 (2013.01); G01N 2333/4716 (2013.01); G01N 2333/70503 (2013.01); Y02A 50/30 (2018.01);
Abstract

Methods and compositions are provided for oligonucleotides that bind targets of interest. The targets include cells and microvesicles, such as those derived from various diseases. The oligonucleotides can be used for diagnostic and therapeutic purposes. The target of the oligonucleotides can be a therapeutic target such as Complement Component 1, Q Subcomponent (C1q) or a subunit thereof.


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