The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 17, 2021

Filed:

Jul. 12, 2018
Applicant:

Kyowa Kirin Co., Ltd., Tokyo, JP;

Inventors:

Hikaru Miyagi, Tokyo, JP;

Michihiko Suzuki, Tokyo, JP;

Junichi Saito, Tokyo, JP;

Hidetsugu Asada, Kyoto, JP;

So Iwata, Kyoto, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 14/705 (2006.01); C07K 14/72 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); C07K 14/705 (2013.01); C07K 14/723 (2013.01); C07K 2317/565 (2013.01); C07K 2319/30 (2013.01); C07K 2319/35 (2013.01);
Abstract

An object of the present invention is to provide a method of enabling efficient structural analysis of a target protein that has been impossible or difficult to analyze so far, by stabilizing the target protein. The present invention provides an anti-BRIL antibody which specifically binds to BRIL or a BRIL fusion protein and an antigen-binding fragment thereof, a nucleic acid encoding the anti-BRIL antibody and the antigen-binding fragment thereof, a vector containing the nucleic acid, an antibody producing cell containing the vector, a method of producing the antibody, and a method of using the antibody in a protein structural analysis.


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