The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 17, 2021
Filed:
Mar. 13, 2019
Applicant:
Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Lianyungang, CN;
Inventors:
Assignee:
Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Lianyungang, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 261/18 (2006.01);
U.S. Cl.
CPC ...
C07D 261/18 (2013.01); C07B 2200/13 (2013.01);
Abstract
Disclosed herein a crystal structure of a caspase inhibitor, and more specifically a crystal structure of an (S)-3-((S)-2-(5-(2-chlorophenyl)isoxazole-3-formylamide)proponamide)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)valeric acid, a preparation method therefor, a crystal polymer, a pharmaceutical composition and uses thereof. The compound A of formula (I) disclosed herein exhibits high crystal structure stability, low hygroscopicity, and advantageously shows physical properties, safety and metabolic stability while having relatively high pharmaceutical value.