The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 17, 2021
Filed:
Jun. 26, 2017
Tianjin Institute of Pharmaceutical Research Co., Ltd., Tianjin, CN;
Guilong Zhao, Tianjin, CN;
Changying Liu, Tianjin, CN;
Yuqiang Liu, Tianjin, CN;
Huihui Chen, Tianjin, CN;
Yuquan Li, Tianjin, CN;
Haizhi Zhang, Tianjin, CN;
Yafei Xie, Tianjin, CN;
Jingwei Wu, Tianjin, CN;
Wei Liu, Tianjin, CN;
Weiren Xu, Tianjin, CN;
Meixiang Zou, Tianjin, CN;
Lida Tang, Tianjin, CN;
TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH CO., LTD., Tianjin, CN;
Abstract
Provided is a method for preparing a URAT1 inhibitor, 2-((5-bromo-4-((4-bromonaphthalen-1-yl)methyl)-4H-1,2,4-triazol-3-yl)thio) acetic acid represented by the following formula ZXS-BR, the reaction equation of which being shown as follows. Compared with the prior art, the preparation method provided by the present application is of low cost, ease of handling, ease of quality control, and applicable to industrialization.