The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11090626 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 17, 2021

Filed:

Feb. 22, 2017
Applicants:

Midatech Ltd., Abingdon, GB;

Midatech Pharma (Wales) Limited, South Glamorgan, GB;

Inventors:

Daniel Palmer, Cardiff, GB;

Rhian Groves, Cardiff, GB;

Paul Seaman, Cardiff, GB;

Victoria Cavalier-Hirth, Cardiff, GB;

Alessandro Pace, Abingdon, GB;

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01J 13/04 (2006.01); B01J 13/02 (2006.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
B01J 13/04 (2013.01); A61K 47/6923 (2017.08); A61K 47/6929 (2017.08); B01J 13/02 (2013.01);
Abstract

The present invention provides a process for producing nanoparticles, comprising: providing a first liquid comprising a metal salt and at least one species of ligand having a functional group capable of binding to a metal surface, providing a second liquid comprising a reducing agent; providing at least one liquid droplet generator operable to generate liquid droplets, causing the at least one liquid droplet generator to form liquid droplets of the first liquid, passing the liquid droplets through a gas to contact the second liquid so as to cause the metal salt and the at least one species of ligand to come into contact with the reducing agent, thereby causing self-assembly of nanoparticles, said nanoparticles having a core of said metal and a corona comprising a plurality of said ligands covalently bound to the core. Also provided are nanoparticles produced by the process of the invention and use of such nanoparticles in medicine.


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