The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 17, 2021
Filed:
Sep. 01, 2016
Oncoqr ML Gmbh, Vienna, AT;
Geert Mudde, Breitenfurt, AT;
Jorge Sepulveda, Vienna, AT;
Christopher Taus, Vienna, AT;
Liesbeth Mudde-Boer, Breitenfurt, AT;
ONCOQR ML GMBH, Tullnerbach, AT;
Abstract
A connector of a helical coiled coil-type structure connecting a first and a second molecule, wherein the first molecule comprises a peptidic first alpha-helix and the second molecule comprises a peptidic second alpha-helix, which second alpha-helix is coiled to the first alpha-helix. The first alpha-helix comprises a C-terminal region consisting of a repeat of an amino acid motif a-xand the C-terminal motif a-x-x, or an N-terminal region consisting of a repeat of an amino acid motif x-a and the N-terminal motif x-x-a, where a is a motif sequence of 4-8 amino acids, xis Lysine, and xis an extension of the motif. The extension consists of 1-10 amino acids and does not comprise more than 4 consecutive amino acids incorporated in said motif a-xor x-a. In a multimeric protein, two polypeptide chains can be connected to each other by such connector.