The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 17, 2021
Filed:
Oct. 06, 2016
Applicant:
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);
Inventors:
David W. Scott, Bethesda, MD (US);
Yongchan Kim, Rockville, MD (US);
Aihong Zhang, Ellicott City, MD (US);
Assignee:
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); C12N 5/07 (2010.01); C07K 14/755 (2006.01); C12N 5/0783 (2010.01); A61P 37/06 (2006.01); A61K 39/00 (2006.01); A61P 21/04 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0008 (2013.01); A61K 35/17 (2013.01); A61P 3/10 (2018.01); A61P 21/04 (2018.01); A61P 37/06 (2018.01); C12N 5/0637 (2013.01); C12N 5/0638 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/5158 (2013.01); C12N 2502/1107 (2013.01); C12N 2510/00 (2013.01);
Abstract
Described herein are agents and methods for targeting antigen-specific B cells using engineered T cells, such as regulatory T cells or cytotoxic T cells, or bi-specific antibodies. The agents and methods can be used to reduce undesirable immune responses.