The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 17, 2021

Filed:

Aug. 05, 2016
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Thomas Jozefiak, Belmont, MA (US);

Michael Parlato, Baltimore, MD (US);

Pratik Patel, Worcester, MA (US);

Kevin Colbert, Baltimore, MD (US);

Ashish Nimgaonkar, Baltimore, MD (US);

Pankaj Pasricha, Ellicott City, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/02 (2006.01); A61K 31/722 (2006.01); A61K 31/79 (2006.01); A61K 47/32 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 47/36 (2006.01); A61K 47/38 (2006.01); A61K 47/34 (2017.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); A61K 9/50 (2006.01); A61K 47/26 (2006.01); A61K 9/06 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 38/02 (2013.01); A61K 9/0095 (2013.01); A61K 9/06 (2013.01); A61K 9/08 (2013.01); A61K 9/16 (2013.01); A61K 9/20 (2013.01); A61K 9/50 (2013.01); A61K 31/722 (2013.01); A61K 31/79 (2013.01); A61K 47/26 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01); A61K 9/48 (2013.01);
Abstract

The present invention provides compositions and methods for treatment of metabolic syndromes. Namely, the presently disclosed compositions and methods are provided for affecting the function of the gastrointestinal endocrine system in key regions of the gut, thereby, producing therapeutic effects on obesity, diabetes and other metabolic disorders. The compositions include components for forming luminal barriers within the gastrointestinal tract of a subject where the barrier is created in-situ via interaction of resident mucin with the mucin-interacting agent.


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