The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 17, 2021
Filed:
May. 23, 2016
Applicant:
Regen Biopharma, Inc, La Mesa, CA (US);
Inventors:
David Koos, La Mesa, CA (US);
Thomas Ichim, San Diego, CA (US);
Assignee:
Regen Biopharma, Inc., La Mesa, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/15 (2015.01); A61K 38/10 (2006.01); A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); A61K 38/10 (2013.01); A61K 38/16 (2013.01);
Abstract
Disclosed are antigen specific cancer vaccines in which immunogenic epitopes are produced intracellularly by administration of modified mRNA encoding said immunogenic epitopes. In one embodiment of the invention, said modified mRNA encodes peptides derived from the protein survivin. By directly inducing gene expression of the antigens to which an immune response is desired, immunogenic peptides are generated intracellularly, thus allowing for a wider repertoire of epitopes to be presented to the adaptive immune system, which augments likelihood of successful induction of immunity.