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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11090313 B1

PDFFull Text
Date of Patent:
Aug. 17, 2021

Filed:

Oct. 23, 2019

Methods for inhibiting muscle atrophy

Applicants:

University of Iowa Research Foundation, Iowa City, IA (US);

The United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Christopher M. Adams, Iowa City, IA (US);

Steven D. Kunkel, West Richland, WA (US);

Michael Welsh, Riverside, IA (US);

Assignees:

UNIVERSITY OF IOWA RESEARCH FOUNDATION, Iowa City, IA (US);

THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, Washington, DC (US);

Attorney:

Heslin Rothenberg Farley & Mesiti P.C.

Primary Examiner:

Dennis Heyer

Int. Cl.
CPC ...
A61K 31/58 (2006.01); A61K 31/436 (2006.01); A61K 31/215 (2006.01); A61K 31/352 (2006.01); A61K 31/36 (2006.01); A61K 31/382 (2006.01); A61K 31/404 (2006.01); A61K 31/4164 (2006.01); A61K 31/4166 (2006.01); A61K 31/4355 (2006.01); A61K 31/4365 (2006.01); A61K 31/437 (2006.01); A61K 31/4375 (2006.01); A61K 31/438 (2006.01); A61K 31/4706 (2006.01); A61K 31/56 (2006.01); A61K 31/353 (2006.01); A61K 31/407 (2006.01); A61K 31/435 (2006.01); A61K 31/473 (2006.01); A61K 31/565 (2006.01); G01N 33/50 (2006.01); C12Q 1/6809 (2018.01);
U.S. Cl.
CPC ...
A61K 31/58 (2013.01); A61K 31/215 (2013.01); A61K 31/352 (2013.01); A61K 31/353 (2013.01); A61K 31/36 (2013.01); A61K 31/382 (2013.01); A61K 31/404 (2013.01); A61K 31/407 (2013.01); A61K 31/4164 (2013.01); A61K 31/4166 (2013.01); A61K 31/435 (2013.01); A61K 31/436 (2013.01); A61K 31/437 (2013.01); A61K 31/438 (2013.01); A61K 31/4355 (2013.01); A61K 31/4365 (2013.01); A61K 31/4375 (2013.01); A61K 31/473 (2013.01); A61K 31/4706 (2013.01); A61K 31/56 (2013.01); A61K 31/565 (2013.01); C12Q 1/6809 (2013.01); G01N 33/5023 (2013.01); C12Q 2600/136 (2013.01); G01N 2800/10 (2013.01); G01N 2800/52 (2013.01);
Abstract

The invention provides a method for (a) increasing skeletal muscle mass; (b) reducing skeletal muscle atrophy; (c) increasing muscular strength; (d) promoting muscle growth; (e) decreasing muscle wasting; or (f) increasing strength per unit of muscle mass in an animal identified or having been identified to be in need of one or more of (a)-(f), the method comprising administering to the animal an effective amount of a compound of formula: or a stereoisomer, solvate, or pharmaceutically acceptable salt thereof, thereby accomplishing one or more of (a)-(f).

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