The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 17, 2021
Filed:
Oct. 18, 2019
Applicant:
National Institute of Biological Sciences, Beijing, Beijing, CN;
Inventors:
Xiaodong Wang, Beijing, CN;
Dianrong Li, Beijing, CN;
Lingjun Meng, Beijing, CN;
Zhiyuan Zhang, Beijing, CN;
Assignee:
National Institute of Biological Sciences, Beijing, Beijing, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/52 (2006.01); A61K 31/522 (2006.01); A61P 15/08 (2006.01); A61K 31/165 (2006.01); A61K 31/17 (2006.01); A61K 31/18 (2006.01); A61K 31/341 (2006.01); A61K 31/381 (2006.01); A61K 31/396 (2006.01); A61K 31/397 (2006.01); A61K 31/40 (2006.01); A61K 31/415 (2006.01); A61K 31/426 (2006.01); A61K 31/44 (2006.01); A61K 31/4453 (2006.01); A61K 31/47 (2006.01); A61K 31/5375 (2006.01);
U.S. Cl.
CPC ...
A61K 31/522 (2013.01); A61K 31/165 (2013.01); A61K 31/17 (2013.01); A61K 31/18 (2013.01); A61K 31/341 (2013.01); A61K 31/381 (2013.01); A61K 31/396 (2013.01); A61K 31/397 (2013.01); A61K 31/40 (2013.01); A61K 31/415 (2013.01); A61K 31/426 (2013.01); A61K 31/44 (2013.01); A61K 31/4453 (2013.01); A61K 31/47 (2013.01); A61K 31/5375 (2013.01); A61P 15/08 (2018.01);
Abstract
The invention provides methods of treating male reproductive senescence comprising administering to a male in need thereof a necroptosis inhibitor, including inhibitors of RIP1, RIP3 or MLKL. The invention also provides pharmaceutical compositions comprising a necroptosis inhibitor and a second different drug for treating male senescence.