The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 2021
Filed:
Jun. 02, 2017
Applicant:
Samsung Life Public Welfare Foundation, Seoul, KR;
Inventors:
Do-Hyun Nam, Seoul, KR;
Jae Hyun Lee, Gyeonggi-do, KR;
Assignee:
AIMED BIO INC., Seoul, KR;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); G01N 33/68 (2006.01); A01K 67/027 (2006.01); C07K 16/28 (2006.01); G01N 33/50 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6854 (2013.01); A01K 67/0271 (2013.01); A61P 35/00 (2018.01); C07K 16/2863 (2013.01); G01N 33/5011 (2013.01); A01K 2207/12 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01); A01K 2267/0387 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); G01N 2500/10 (2013.01);
Abstract
The present disclosure relates to a method of screening an anti-NRP1 antibody or an antigen-binding fragment thereof by use of patient-derived tumor spheroids overexpressing NRP1 and an animal model comprising the same, and more particularly to a method of screening an antibody or an antigen-binding fragment thereof through in vitro and in vivo panning by use of a patient-derived tumor spheroid containing NRP1 and an animal model transplanted with the same, respectively.