The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 2021
Filed:
Dec. 13, 2018
Applicant:
Immundiagnostik Ag, Bensheim, DE;
Inventors:
Franz Paul Armbruster, Bobenheim-Roxheim, DE;
Moritz Leppkes, Nuremberg, DE;
Assignee:
Immundiagnostik AG, Bensheim, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 33/564 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54313 (2013.01); G01N 33/564 (2013.01); G01N 33/6854 (2013.01);
Abstract
A method for detecting and quantifying anti-neutrophil-cytoplasmic antibodies (ANCA) in a sample of bodily fluid from a patient suspected of suffering from an autoimmune disease, including the steps of contacting human polymorphonuclear neutrophils able to release extracellular traps (NETs) with microspheres to produce NET-coated microspheres, contacting the NET-coated microspheres with the sample of bodily fluid, and labeling and subsequent analyzing of anti-neutrophil-cytoplasmic antibodies by flow cytometric methods.