The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 10, 2021

Filed:

Apr. 28, 2017
Applicant:

Saint Louis University, St. Louis, MO (US);

Inventors:

Sergio Barranco-Medina, Manchester, MO (US);

Enrico Di Cera, Ladue, MO (US);

Nicola Pozzi, St. Louis, MO (US);

Assignee:

Saint Louis University, St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/74 (2006.01); A61K 9/00 (2006.01); C07K 14/745 (2006.01); C12N 15/62 (2006.01); A61P 7/02 (2006.01); A61K 38/36 (2006.01); A61K 38/48 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/6429 (2013.01); A61K 9/0019 (2013.01); A61K 38/366 (2013.01); A61K 38/4833 (2013.01); A61K 45/06 (2013.01); A61P 7/02 (2018.01); C07K 14/7455 (2013.01); C12N 15/62 (2013.01); C12Y 304/21005 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01);
Abstract

Compositions and methods for regulating the blood coagulation pathway are disclosed. More particularly, the present disclosure relates to thrombin-thrombomodulin fusion proteins and their use as blood anticoagulants and for treating sepsis.


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