The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 2021
Filed:
Apr. 07, 2017
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Seulki Lee, Elkridge, MD (US);
Martin G. Pomper, Baltimore, MD (US);
Ogyi Park, Elkridge, MD (US);
Magdalena Scully, Mount Airy, MD (US);
Pankaj J. Pasricha, Ellicott City, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 38/19 (2006.01); C07K 16/28 (2006.01); A61K 47/60 (2017.01); A61K 38/17 (2006.01); A61P 1/18 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 9/0019 (2013.01); A61K 38/177 (2013.01); A61K 47/60 (2017.08); A61P 1/18 (2018.01); A61K 38/19 (2013.01); C07K 2317/21 (2013.01); C07K 2317/73 (2013.01); C07K 2317/75 (2013.01);
Abstract
Death receptor 5 (DR5) agonist compositions and methods for treating pancreatitis have been developed. The compositions include Tumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL), its analogues, and anti-DR5 agonistic antibodies. In certain embodiments, TRAIL analogs and anti-death receptor 5 agonistic antibodies have analgesic and disease modifying effects on the pancreas.