The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 2021
Filed:
Dec. 15, 2017
Institute for Research IN Biomedicine, Bellinzona, CH;
The Pirbright Institute, Surrey, GB;
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Rockville, MD (US);
Lei Chen, Bethesda, MD (US);
Baoshan Zhang, Bethesda, MD (US);
Peter D. Kwong, Bethesda, MD (US);
Davide Corti, Bellinzona, CH;
Antonio Lanzavecchia, Porza, CH;
Geraldine Taylor, Berkshire, GB;
THE PIRBRIGHT INSTITUTE, Surrey, GB;
INSTITUTE FOR RESEARCH IN BIO-MEDICINE, Bellinzona, CH;
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, Rockville, MD (US);
Abstract
The present invention provides immunogens comprising a recombinant Respiratory Syncytial Virus (RSV) F protein stabilized in a prefusion conformation and nucleic acids encoding such immunogens. In particular the present invention provides polypeptides, polynucleotides, compositions, and uses thereof for eliciting an immune response to bovine respiratory syncytial virus (bRSV). Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject.