The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 10, 2021

Filed:

Feb. 10, 2017
Applicant:

Stokes Bio Limited, Limerick, IE;

Inventors:

Mark Davies, Limerick, IE;

Tara Dalton, Limerick, IE;

Assignee:

STOKES BIO LTD., Limerick, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 7/00 (2006.01); B01L 3/00 (2006.01); G01N 21/64 (2006.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
B01L 7/525 (2013.01); B01L 3/502715 (2013.01); B01L 3/502784 (2013.01); C12Q 1/686 (2013.01); G01N 21/6428 (2013.01); B01L 3/5027 (2013.01); B01L 2200/0673 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0838 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/18 (2013.01); B01L 2300/185 (2013.01); B01L 2300/1822 (2013.01); B01L 2400/0487 (2013.01); G01N 2201/0826 (2013.01); G01N 2201/0833 (2013.01);
Abstract

A biological sample analysis system including a sample preparation system forming droplets of segmented sample separated by a carrier fluid immiscible with the sample. The droplets include reaction mixtures for amplification of at least one target nucleic acid. A thermal cycling device having a sample block having a plurality of controlled thermal zones, and a containment structure in thermal communication with the plurality of controlled thermal zones. The containment structure receives and contains the droplets of segmented sample separated by the immiscible carrier fluid from the sample preparation system. A controller for controlling a temperature in each thermal zone of the sample block. A detection system detects electromagnetic radiation emitted from each of the droplets individually from the queue of droplets as they flow past the detection system. A positioning system to facilitate moving a queue of the droplets in the thermal cycling device relative to the detection system.


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