The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 10, 2021

Filed:

Sep. 12, 2017
Applicant:

Heron Therapeutics, Inc., Redwood City, CA (US);

Inventors:

Thomas B. Ottoboni, Belmont, CA (US);

Lee Ann Lynn Girotti, San Bruno, CA (US);

Assignee:

Heron Therapeutics, Inc., San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); A61K 45/06 (2006.01); A61K 47/20 (2006.01); A61K 9/127 (2006.01); A61K 47/34 (2017.01); A61K 31/5415 (2006.01); A61K 47/14 (2017.01); A61K 47/12 (2006.01); A61K 9/00 (2006.01); A61K 31/196 (2006.01); A61K 9/14 (2006.01); A61K 31/00 (2006.01); A61K 47/32 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 9/0019 (2013.01); A61K 9/0024 (2013.01); A61K 9/0085 (2013.01); A61K 9/127 (2013.01); A61K 9/14 (2013.01); A61K 31/00 (2013.01); A61K 31/196 (2013.01); A61K 31/445 (2013.01); A61K 31/5415 (2013.01); A61K 47/12 (2013.01); A61K 47/14 (2013.01); A61K 47/20 (2013.01); A61K 47/32 (2013.01);
Abstract

Compositions comprised of a delivery vehicle or delivery system and an active agent dispersed within the delivery vehicle or system, wherein the delivery vehicle or system contains a polyorthoester polymer and a polar aprotic solvent. Also disclosed are low viscosity delivery systems for administration of active agents. The low viscosity delivery systems have a polyorthoester polymer, a polar aprotic solvent and a solvent containing a triglyceride viscosity reducing agent. Compositions described include an amide- or anilide-type local anesthetic of the 'caine' classification, and a non-steroidal anti-inflammatory drug (NSAID), along with related methods, e.g., for treatment of post-operative pain or for prophylactic treatment of pain. The compositions are suitable for delivery via, e.g., direct application and instillation, intradermal injection, subcutaneous injection, and nerve block (perineural).


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